CH3OCO-D-CHA-Gly-Arg-pNA acetate

• CAT Number: I040914
• CAS Number: 80895-10-9
• Molecular Formula: C27H42N8O9
• Molecular Weight: 622.67
• Purity: ≥95%
• Synonyms: acetic acid;methyl N-[(2R)-3-cyclohexyl-1-[[2-[[(2S)-5-(diaminomethylideneamino)-1-(4-nitroanilino)-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxopropan-2-yl]carbamate
• InChI: InChI=1S/C25H38N8O7.C2H4O2/c1-40-25(37)32-20(14-16-6-3-2-4-7-16)22(35)29-15-21(34)31-19(8-5-13-28-24(26)27)23(36)30-17-9-11-18(12-10-17)33(38)39;1-2(3)4/h9-12,16,19-20H,2-8,13-15H2,1H3,(H,29,35)(H,30,36)(H,31,34)(H,32,37)(H4,26,27,28);1H3,(H,3,4)/t19-,20+;/m0./s1
• InChIKey: QXWRKXQCMBOLJR-CMXBXVFLSA-N
• SMILES: CC(=O)O.COC(=O)NC(CC1CCCCC1)C(=O)NCC(=O)NC(CCCN=C(N)N)C(=O)NC2=CC=C(C=C2)[N+](=O)[O-]

CH3OCO-D-CHA-Gly-Arg-pNA acetate is a chromogenic substrate for factor Xa[1][2].

Reference

[1]. Muthiah Manoharan, et al. Preparation of lipids and glycolipids for the delivery of therapeutics to cells. Patent. US20180064807.

[2]. Patil DN, et al. Structural basis for dual inhibitory role of tamarind Kunitz inhibitor (TKI) against factor Xa and trypsin. FEBS J. 2012 Dec;279(24):4547-64.
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