Chaetochromin C

For research use only. Not for therapeutic Use.

  • CAT Number: I024510
  • CAS Number: 108906-68-9
  • Molecular Formula: C29H24O10
  • Molecular Weight: 532.5
  • Purity: 98%
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Chaetochromin C also known as 4548-G05, is an orally active, small-molecule, selective agonist of the insulin receptor.


Catalog Number I024510
CAS Number 108906-68-9
Synonyms

Chaetochromin C; UNII-IXY515E9BM

Molecular Formula C29H24O10
Purity 98%
Solubility Soluble in DMSO
Appearance Solid powder
Storage Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
IUPAC Name (2R,2'R,3R)-5,5',6,6',8,8'-hexahydroxy-2,2',3-trimethyl-2,2',3,3'-tetrahydro-4H,4'H-[9,9'-bibenzo[g]chromene]-4,4'-dione
InChI InChI=1S/C29H24O10/c1-9-4-14(30)25-19(38-9)5-12-21(15(31)7-17(33)23(12)28(25)36)22-13-6-20-26(27(35)10(2)11(3)39-20)29(37)24(13)18(34)8-16(22)32/h5-11,31-34,36-37H,4H2,1-3H3/t9-,10-,11-/m1/s1
InChIKey ZHECJFNKDQXHIW-GMTAPVOTSA-N
SMILES C[C@@H]1CC(c(c2O)c(O1)cc3c2c(O)cc(O)c3c(c(O)cc4O)c5c4c(O)c(C([C@@H]([C@H](O6)C)C)=O)c6c5)=O
Reference

1: Paranagama PA, Wijeratne EM, Gunatilaka AA. Uncovering biosynthetic potential of plant-associated fungi: effect of culture conditions on metabolite production by Paraphaeosphaeria quadriseptata and Chaetomium chiversii. J Nat Prod. 2007 Dec;70(12):1939-45. doi: 10.1021/np070504b. Epub 2007 Dec 6. PMID: 18052326.
2: Koyama K, Natori S. Chaetochromins B, C and D, bis(naphtho-gamma-pyrone) derivatives from Chaetomium gracile. Chem Pharm Bull (Tokyo). 1987 Feb;35(2):578-84. doi: 10.1248/cpb.35.578. PMID: 3594673.

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