Chaetoglobosin A

• CAT Number: I011304
• CAS Number: 50335-03-0
• Molecular Formula: C32H36N2O5
• Molecular Weight: 528.64
• Purity: ≥95%
• Synonyms: (1E,4S,5E,7R,9E,11aR,14S,14aR,15S,15aR,16aS,16bR)-4,7,14,14a,15,15a,16a,16b-Octahydro-7-hydroxy-14-(1H-indol-3-ylmethyl)-4,6,15,15a-tetramethyl-3H-cyclotridec[d]oxireno[f]isoindole-8,11,12(13H)-trione
• Target: Apoptosis
• Solubility: Soluble to 100 mM in DMSO
• Storage: Store at -20℃
• IUPAC Name: (1R,3E,6R,7E,9S,11E,13R,14S,16R,17S,18R,19S)-6-hydroxy-19-(1H-indol-3-ylmethyl)-7,9,16,17-tetramethyl-15-oxa-20-azatetracyclo[11.8.0.01,18.014,16]henicosa-3,7,11-triene-2,5,21-trione
• InChI: InChI=1S/C32H36N2O5/c1-17-8-7-10-22-29-31(4,39-29)19(3)27-24(15-20-16-33-23-11-6-5-9-21(20)23)34-30(38)32(22,27)26(36)13-12-25(35)28(37)18(2)14-17/h5-7,9-14,16-17,19,22,24,27-29,33,37H,8,15H2,1-4H3,(H,34,38)/b10-7+,13-12+,18-14+/t17-,19-,22-,24-,27-,28+,29-,31+,32+/m0/s1
• InChIKey: OUMWCYMRLMEZJH-HSXMBTRQSA-N
• SMILES: C[C@H] C/C=C/[C@H]2[C@H]3[C@](O3)([C@H]([C@@H]4[C@@]2(C(=O)/C=C/C(=O)[C@@H](/C(=C1)/C)O)C(=O)N[C@H]4CC5=CNC6=CC=CC=C65)C)C

Chaetoglobosin A (Cat.No:I011304) is a fungal metabolite with potent cytotoxic and antifungal properties. It exhibits inhibitory activity against various cancer cell lines by disrupting microtubule assembly and inducing cell cycle arrest. Additionally, it has shown antifungal activity against pathogenic fungi. Chaetoglobosin A holds promise as a potential therapeutic agent for cancer and fungal infections, although further research is needed to explore its clinical applications.