Chebulagic acid

For research use only. Not for therapeutic Use.

  • CAT Number: I002760
  • CAS Number: 23094-71-5
  • Molecular Formula: C41H30O27
  • Molecular Weight: 954.66
  • Purity: ≥95%
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Chebulagic acid (Cat.No:I002760) is a natural compound found in Terminalia chebula, a medicinal plant commonly used in traditional medicine. It exhibits a wide range of biological activities, including antioxidant, anti-inflammatory, and anticancer properties. Chebulagic acid has shown potential in the treatment of various diseases, such as diabetes, cardiovascular disorders, and certain types of cancer. Its diverse pharmacological effects make it a promising candidate for further research and drug development.


Catalog Number I002760
CAS Number 23094-71-5
Molecular Formula C41H30O27
Purity ≥95%
Target Metabolic Enzyme/Protease
Storage 3 years -20℃ powder
IUPAC Name 2-[13,14,15,18,19,20,31,35,36-nonahydroxy-2,10,23,28,32-pentaoxo-5-(3,4,5-trihydroxybenzoyl)oxy-3,6,9,24,27,33-hexaoxaheptacyclo[28.7.1.04,25.07,26.011,16.017,22.034,38]octatriaconta-1(37),11,13,15,17,19,21,34(38),35-nonaen-29-yl]acetic acid
InChI InChI=1S/C41H30O27/c42-13-1-8(2-14(43)24(13)49)35(56)68-41-34-33-31(64-39(60)12(6-19(47)48)22-23-11(38(59)67-34)5-17(46)27(52)32(23)65-40(61)30(22)55)18(63-41)7-62-36(57)9-3-15(44)25(50)28(53)20(9)21-10(37(58)66-33)4-16(45)26(51)29(21)54/h1-5,12,18,22,30-31,33-34,41-46,49-55H,6-7H2,(H,47,48)
InChIKey HGJXAVROWQLCTP-UHFFFAOYSA-N
SMILES C1C2C3C(C(C(O2)OC(=O)C4=CC(=C(C(=C4)O)O)O)OC(=O)C5=CC(=C(C6=C5C(C(C(=O)O3)CC(=O)O)C(C(=O)O6)O)O)O)OC(=O)C7=CC(=C(C(=C7C8=C(C(=C(C=C8C(=O)O1)O)O)O)O)O)O
Reference

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<br>[1]. Athira AP et al. Inhibition of Angiogenesis In Vitro by Chebulagic Acid: A COX-LOX Dual Inhibitor. Int J Vasc Med. 2013;2013:843897.

<br>[2]. Kim HJ et al. Neuroprotective Effect of Chebulagic Acid via Autophagy Induction in SH-SY5Y Cells.
Biomol Ther (Seoul). 2014 Jul;22(4):275-81.

<br>[3]. Liu Y et al. Chebulagic acid inhibits the LPS-induced expression of TNF-α and IL-1β in endothelial cells by suppressing MAPK activation. Exp Ther Med. 2015 Jul;10(1):263-268.

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