CHF-2993

• CAT Number: I005942
• CAS Number: 202914-21-4
• Molecular Formula: C12H16N2O2
• Molecular Weight: 220.272
• Purity: ≥95%
• Synonyms: CHF-2993; CHF2993; CHF 2993; UNII-5NY5Q1OUZ3; 5NY5Q1OUZ3.;(S)-2-((2,3-dihydro-1H-inden-2-yl)amino)-3-hydroxypropanamide
• Solubility: Soluble in DMSO, not in water
• Storage: 0 - 4°C for short term ,or -20 °C for long term
• IUPAC Name: (2S)-2-(2,3-dihydro-1H-inden-2-ylamino)-3-hydroxypropanamide
• InChI: InChI=1S/C12H16N2O2/c13-12(16)11(7-15)14-10-5-8-3-1-2-4-9(8)6-10/h1-4,10-11,14-15H,5-7H2,(H2,13,16)/t11-/m0/s1
• InChIKey: MZRNXGZQIIFZTC-NSHDSACASA-N
• SMILES: C1C(CC2=CC=CC=C21)NC(CO)C(=O)N

CHF-2993 (Cat No.: I005942) is a long-acting muscarinic antagonist (LAMA) developed for the treatment of respiratory conditions such as chronic obstructive pulmonary disease (COPD). It works by selectively blocking M3 muscarinic receptors in the airway smooth muscle, leading to prolonged bronchodilation and improved airflow. CHF-2993 is designed for inhalation, offering sustained efficacy with once-daily dosing. Its high receptor affinity, long duration of action, and favorable safety profile make it a promising candidate for managing chronic respiratory diseases and enhancing patient adherence to therapy.