Chimeric Rabies Virus Glycoprotein Fragment (RVG-9R)

• CAT Number: I041861
• CAS Number: 1678417-57-6
• Molecular Formula: C201H334N82O55S2
• Molecular Weight: 4843.45
• Purity: ≥95%

Chimeric Rabies Virus Glycoprotein Fragment (RVG-9R), a chimeric peptide consisting of 29 amino acids, is synthesized by adding nona-arginine motif to the carboxy terminus of RVG (rabies virus glycoprotein). Chimeric Rabies Virus Glycoprotein Fragment (RVG-9R) is positively charged and able to bind negatively charged nucleic acids via charge interaction[1][2].

Reference

[1]. Rassu G, et al. Nose-to-brain delivery of BACE1 siRNA loaded in solid lipid nanoparticles for Alzheimer’s therapy. Colloids Surf B Biointerfaces. 2017 Apr 1;152:296-301.
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[2]. Margus H, et al. Cell-penetrating peptides as versatile vehicles for oligonucleotide delivery. Mol Ther. 2012 Mar;20(3):525-33.
 [Content Brief]