For research use only. Not for therapeutic Use.
Chloramphenicol 3-Acetate (Cat. No: R032047) is a chloramphenicol derivative found in the metabolic decomposition of chloramphenicol by Alcaligenes faecalis. At the same time, chloramphenicol acetate, as the main product of chloramphenicol acetyltransferase, is involved in the main resistance mechanism of chloramphenicol.
| Catalog Number | R032047 |
| CAS Number | 10318-16-8 |
| Synonyms | 3-Acetoxychloramphenicol; 3-Acetylchloramphenicol; 3-O-Monoacetylchloramphenicol; [R-(R*,R*)]-N-[1-[(acetyloxy)methyl]-2-hydroxy-2-(4-nitrophenyl)ethyl]-2,2-dichloroacetamide; D-threo-(-)-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-nitrophenethyl] |
| Molecular Formula | C13H14Cl2N2O6 |
| Purity | 99% |
| Appearance | White solid |
| Storage | Store at -20°C |
| Analysis method | HPLC |
| IUPAC Name | [(2R,3R)-2-[(2,2-dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl] acetate |
| InChI | InChI=1S/C13H14Cl2N2O6/c1-7(18)23-6-10(16-13(20)12(14)15)11(19)8-2-4-9(5-3-8)17(21)22/h2-5,10-12,19H,6H2,1H3,(H,16,20)/t10-,11-/m1/s1 |
| InChIKey | VVOIFRARHIZCJD-GHMZBOCLSA-N |
| SMILES | CC(=O)OCC(C(C1=CC=C(C=C1)[N+](=O)[O-])O)NC(=O)C(Cl)Cl |
| Reference | Isolation of 3′-O-acetylchloramphenicol: A possible intermediate in chloramphenicol biosynthesis. Gross F. et al. Bioorg. Med. Chem. Letters 2002, 12, 283.<br /> |
