For research use only. Not for therapeutic Use.
Chlorcyclizine is a first-generation antihistamine of the phenylpiperazine class marketed in the United States and certain other countries. It is used primarily to treat allergy symptoms such as rhinitis, urticaria, and pruritus, and may also be used as an antiemetic. In addition to its antihistamine effects, chlorcyclizine also has some anticholinergic, antiserotonergic, and local anesthetic properties. It also has been studied as a potential treatment for hepatitis C.
| Catalog Number | I006104 |
| CAS Number | 1620-21-9 (HCl salt); 82-93-9 (free base). |
| Synonyms | Di-Paralene, Mantadil, Pruresidine, Trihistan, Chlorcyclizine; Chlorcyclizine HCl; Chlorcyclizine hydrochloride.;1-((4-chlorophenyl)(phenyl)methyl)-4-methylpiperazine hydrochloride |
| Molecular Formula | C18H22Cl2N2 |
| Purity | ≥95% |
| Solubility | Soluble in DMSO, not in water |
| Storage | 0 - 4°C for short term ,or -20 °C for long term |
| SMILES | CN1CCN(C(C2=CC=C(Cl)C=C2)C3=CC=CC=C3)CC1.[H]Cl |
| Reference | </br> 1:He S, Xiao J, Dulcey AE, Lin B, Rolt A, Hu Z, Hu X, Wang AQ, Xu X, Southall N, Ferrer M, Zheng W, Liang TJ, Marugan JJ. Discovery, Optimization, and Characterization of Novel Chlorcyclizine Derivatives for the Treatment of Hepatitis C Virus Infection. J Med Chem. 2015 Nov 24. [Epub ahead of print] PubMed PMID: 26599718. |
