For research use only. Not for therapeutic Use.
Chlormidazole Hydrochloride, also known as H-115 and Myco-polycid, is an imidazole antifungal used to treat cutaneous fungal infections.
| Catalog Number | I006106 |
| CAS Number | 54118-67-1(HCl) |
| Synonyms | Chlormidazole Hydrochloride; H115; H 115; H-115; Myco-polycid; Futrican hydrochloride; Fungo-polycid;1-(4-chlorobenzyl)-2-methyl-1H-benzo[d]imidazole hydrochloride |
| Molecular Formula | C15H14Cl2N2 |
| Purity | ≥95% |
| Solubility | Soluble in DMSO |
| Storage | 0 - 4°C for short term ,or -20 °C for long term |
| IUPAC Name | 1-[(4-chlorophenyl)methyl]-2-methylbenzimidazole;hydrochloride |
| InChI | InChI=1S/C15H13ClN2.ClH/c1-11-17-14-4-2-3-5-15(14)18(11)10-12-6-8-13(16)9-7-12;/h2-9H,10H2,1H3;1H |
| InChIKey | MHMTXDMLQZHXRZ-UHFFFAOYSA-N |
| SMILES | CC1=NC2=CC=CC=C2N1CC3=CC=C(C=C3)Cl.Cl |
| Reference | 1:Pol Tyg Lek. 1990 Jan 22-29;45(4-5):91-2. [Sensitivity of aerobic bacteria and Candida species to chlormidazole hydrochloride in vitro].Krasiejko I,Gajewicz L,Lipnicki D, PMID: 2395759 </br><span>Abstract:</span> Over 100 bacterial stains, including Candida sp., gram-positive cocci and some gram-negative bacilli, were tested. The majority of microorganisms was isolated from man. Only one bacterial strain (5 micrograms/mL) and 76% of Candida strains were sensitive to chlormidazole HCl (10 micrograms/mL). It may be assumed that most infections with Candida sp. will respond to therapy with drugs containing chlormidazole HCl. Relatively simple and inexpensive tube test may serve to evaluate microbial sensitivity to this agent, especially in case of isolates from patients. |
