For research use only. Not for therapeutic Use.
Chloro Sofosbuvir(Cat No.:R026732)is a derivative of Sofosbuvir, a nucleotide analog prodrug used for the treatment of hepatitis C virus (HCV) infections. This compound is studied for its structural modifications, which provide insights into the chemical properties and biological activity of Sofosbuvir analogs. Chloro Sofosbuvir is valuable in pharmaceutical research for understanding the role of halogenated derivatives in enhancing drug stability, efficacy, or pharmacokinetics. It aids in exploring novel antiviral agents and optimizing therapeutic strategies for HCV treatment while supporting studies on resistance mechanisms and drug development.
Catalog Number | R026732 |
CAS Number | 1496552-51-2 |
Synonyms | N-[[P(S),2’R]-2’-Chloro-2’-deoxy-2’-methyl-P-phenyl-5’-uridylyl]-L-alanine 1-Methylethyl Ester? |
Molecular Formula | C₂₂H₂₉ClN₃O₉P |
Purity | ≥95% |
Target | HCV |
Storage | -20°C |
IUPAC Name | propan-2-yl 2-[[[4-chloro-5-(2,4-dioxopyrimidin-1-yl)-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate |
InChI | InChI=1S/C22H29ClN3O9P/c1-13(2)33-19(29)14(3)25-36(31,35-15-8-6-5-7-9-15)32-12-16-18(28)22(4,23)20(34-16)26-11-10-17(27)24-21(26)30/h5-11,13-14,16,18,20,28H,12H2,1-4H3,(H,25,31)(H,24,27,30) |
InChIKey | SFPFZQKYPOWCSI-UHFFFAOYSA-N |
SMILES | CC(C)OC(=O)C(C)NP(=O)(OCC1C(C(C(O1)N2C=CC(=O)NC2=O)(C)Cl)O)OC3=CC=CC=C3 |