For research use only. Not for therapeutic Use.
Chloroquinoxaline sulfonamide（Cat No.:I017257）is a chemical compound used primarily as a veterinary antimicrobial agent. It exhibits broad-spectrum antibacterial properties, particularly against gram-positive and gram-negative bacteria. This sulfonamide derivative is commonly utilized in animal feed to prevent and treat bacterial infections, promoting overall animal health and growth. Its mechanism of action involves inhibiting folic acid synthesis in bacteria, ultimately impairing DNA replication and protein synthesis. Chloroquinoxaline sulfonamide is an important tool in livestock management and disease prevention, ensuring improved productivity and reduced mortality in animal farming.
| Catalog Number | I017257 |
| CAS Number | 97919-22-7 |
| Molecular Formula | C₁₄H₁₁ClN₄O₂S |
| Purity | ≥95% |
| Target | Cell Cycle/DNA Damage |
| IUPAC Name | 4-amino-N-(5-chloroquinoxalin-2-yl)benzenesulfonamide |
| InChI | InChI=1S/C14H11ClN4O2S/c15-11-2-1-3-12-14(11)17-8-13(18-12)19-22(20,21)10-6-4-9(16)5-7-10/h1-8H,16H2,(H,18,19) |
| InChIKey | CTSNHMQGVWXIEG-UHFFFAOYSA-N |
| SMILES | C1=CC2=NC(=CN=C2C(=C1)Cl)NS(=O)(=O)C3=CC=C(C=C3)N |
| Reference | [1]. Gao H, et al. Chloroquinoxaline sulfonamide (NSC 339004) is a topoisomerase IIalpha/beta poison. Cancer Res. 2000 Nov 1;60(21):5937-40.<br>[2]. Branda RF, et al. Cellular pharmacology of chloroquinoxaline sulfonamide and a related compound in murine B16 melanoma cells. Biochem Pharmacol. 1988 Dec 1;37(23):4557-64. |
