For research use only. Not for therapeutic Use.
Chlorphentermine hydrochloride is a serotonin transporter (SERT) substrate with a Ki value of 338 nM for [3H]5-HT uptake.
KEYWORDS: Chlorphentermine hydrochloride | Supplier | SERT substrate | CAS [151-06-4] | [461-78-9] | Serotonin | SERT | Substrate | Proteins | Primary pulmonary hypertension | Appetite suppressant | Obesity | Anorectic agent | 5-HTT
| Catalog Number | M134974 |
| CAS Number | 151-06-4 |
| Molecular Formula | C10H14ClN.HCl |
| Purity | ≥95% |
| IUPAC Name | 1-(4-chlorophenyl)-2-methylpropan-2-amine;hydrochloride |
| InChI | InChI=1S/C10H14ClN.ClH/c1-10(2,12)7-8-3-5-9(11)6-4-8;/h3-6H,7,12H2,1-2H3;1H |
| SMILES | CC(C)(CC1=CC=C(C=C1)Cl)N.Cl |
| Reference | RB Rothman et al. Aminorex, fenfluramine, and chlorphentermine are serotonin transporter substrates. Implications for primary pulmonary hypertension. Circulation. 1999 Aug 24;100(8):869-75. C Lucey at al. Chlorphentermine: a new “appetite suppressant”. A cross-over double-blind trial. Ulster Med J. 1962 Dec 1;31(2):181-4. |
