Cholic Acid

• CAT Number: R012539
• CAS Number: 81-25-4
• Molecular Formula: C24H40O5
• Molecular Weight: 408.61
• Purity: ≥95%
• Synonyms: (3α,5β,7α12α)-3,7,12-Trihydroxy-cholan-24-oic Acid; 17β-(1-Methyl-3-carboxy-propyl)etiocholane-3α,7α,12α-triol;?5β-Cholic Acid; Cholalic Acid; Cholalin; Colalin; NSC-6135
• Target: Endogenous Metabolite
• Storage: Room temperature
• IUPAC Name: (4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
• InChI: InChI=1S/C24H40O5/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29)/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-/m1/s1
• InChIKey: BHQCQFFYRZLCQQ-OELDTZBJSA-N
• SMILES: C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)O)C

Cholic acid(CAT: R012539) is a primary bile acid with the molecular formula C₂₄H₄₀O₅, naturally synthesized in the liver from cholesterol. It appears as a white crystalline powder, sparingly soluble in water but soluble in ethanol and other organic solvents. Cholic acid plays a vital role in the emulsification and absorption of dietary fats and fat-soluble vitamins by forming micelles in the intestine. In medicine, it is used to treat certain bile acid synthesis disorders and peroxisomal disorders. In research, it serves as a biochemical reagent for studying lipid metabolism, bile acid pathways, and micelle formation, as well as a precursor for synthesizing bile acid derivatives.