CHR 6494 trifluoroacetate

• CAT Number: I011168
• CAS Number: 1458630-17-5
• Molecular Formula: C18H17F3N6O2
• Molecular Weight: 406.36
• Purity: ≥95%
• Synonyms: 3-(1H-Indazol-5-yl)-N-propylimidazo[1,2-b]pyridazin-6-amine trifluoroacetate
• Target: Haspin Kinase
• Solubility: Soluble to 100 mM in DMSO
• Storage: Store at +4C
• IUPAC Name: 3-(1H-indazol-5-yl)-N-propylimidazo[1,2-b]pyridazin-6-amine;2,2,2-trifluoroacetic acid
• InChI: InChI=1S/C16H16N6.C2HF3O2/c1-2-7-17-15-5-6-16-18-10-14(22(16)21-15)11-3-4-13-12(8-11)9-19-20-13;3-2(4,5)1(6)7/h3-6,8-10H,2,7H2,1H3,(H,17,21)(H,19,20);(H,6,7)
• InChIKey: ILWYDZNXJQESDI-UHFFFAOYSA-N
• SMILES: CCCNC1=NN2C(=NC=C2C3=CC4=C(C=C3)NN=C4)C=C1.C(=O)(C(F)(F)F)O

CHR 6494 Trifluoroacetate（Cat No.:I011168）is a potent inhibitor of the enzyme lysine-specific demethylase 1 (LSD1), crucial in regulating gene expression through histone methylation. This trifluoroacetate salt form enhances the compound’s solubility and stability, making it suitable for in vitro and in vivo studies. With its potential in cancer therapy, CHR 6494 targets various malignancies by restoring the expression of tumor suppressor genes. Its unique mechanism offers a promising avenue for epigenetic research, making it a valuable tool in pharmaceutical development and the exploration of innovative treatment strategies.