For research use only. Not for therapeutic Use.
ChX710 (CAT: I019707) emerges as a noteworthy compound with the ability to prime the type I interferon response when exposed to cytosolic DNA. This priming results in the activation of the ISRE (Interferon-Stimulated Response Element) promoter sequence, leading to the induction of specific Interferon-Stimulated Genes (ISGs). Moreover, ChX710 triggers the phosphorylation of Interferon Regulatory Factor (IRF) 3, a key transcription factor in the interferon signaling pathway.
| Catalog Number | I019707 |
| CAS Number | 2438721-44-7 |
| Molecular Formula | C₁₈H₂₁N₅O |
| Purity | ≥95% |
| Target | STING |
| Reference | [1]. Khiar S, et al. Identification of a small molecule that primes the type I interferon response to cytosolic DNA. Sci Rep. 2017 May 31;7(1):2561. |
