For research use only. Not for therapeutic Use.
CID 1375606(CAT: I019706) acts as a surrogate agonist for the orphan G protein-coupled receptor GPR27. Specifically designed to target GPR27, CID 1375606 elicits an agonistic response. GPR27, notable for its significant conservation across vertebrates and predominant presence in the central nervous system, has been further associated with insulin secretion, broadening its physiological implications[1]. This compound’s ability to mimic agonistic effects on GPR27 holds potential in shedding light on the receptor’s functions and offers opportunities for exploring its role in various physiological processes, including those within the central nervous system and insulin regulation pathways.
| Catalog Number | I019706 |
| CAS Number | 313493-80-0 |
| Molecular Formula | C₂₀H₁₄Cl₂N₂O₂ |
| Purity | ≥95% |
| Reference | [1]. Dupuis N, et al. Activation of the Orphan G Protein-Coupled Receptor GPR27 by Surrogate Ligands Promotes β-Arrestin 2 Recruitment. Mol Pharmacol. 2017 Jun;91(6):595-608. |
