CID 2011756

• CAT Number: I013940
• CAS Number: 638156-11-3
• Molecular Formula: C₂₂H₂₁ClN₂O₃
• Molecular Weight: 396.87
• Purity: ≥95%
• Target: PKD
• Solubility: 10 mM in DMSO
• IUPAC Name: 5-(3-chlorophenyl)-N-[4-(morpholin-4-ylmethyl)phenyl]furan-2-carboxamide
• InChI: InChI=1S/C22H21ClN2O3/c23-18-3-1-2-17(14-18)20-8-9-21(28-20)22(26)24-19-6-4-16(5-7-19)15-25-10-12-27-13-11-25/h1-9,14H,10-13,15H2,(H,24,26)
• InChIKey: XQJWTJLJEYIUDZ-UHFFFAOYSA-N
• SMILES: C1COCCN1CC2=CC=C(C=C2)NC(=O)C3=CC=C(O3)C4=CC(=CC=C4)Cl

CID 2011756（Cat No.:I013940）is a small molecule inhibitor identified through chemical screening as a potential therapeutic agent targeting the enzyme glycogen synthase kinase-3β (GSK-3β). GSK-3β is involved in regulating various cellular processes, including metabolism, cell cycle, and neurodegeneration. By inhibiting GSK-3β, CID 2011756 may have applications in treating conditions such as Alzheimer’s disease, Parkinson’s disease, and other neurodegenerative disorders. It may also hold promise in regulating insulin signaling, with potential uses in diabetes. However, further studies and clinical trials are needed to evaluate its efficacy, safety, and therapeutic potential.

Reference

[1]. Sharlow ER, et al. Discovery of diverse small molecule chemotypes with cell-based PKD1 inhibitory activity. PLoS One. 2011;6(10):e25134.