CID-5721353

• CAT Number: I006131
• CAS Number: 301356-95-6
• Molecular Formula: C15H9BrN2O6S2
• Molecular Weight: 457.269
• Purity: ≥95%
• Synonyms: CID5721353; CID-5721353; CID 5721353; BCL6 Inhibitor, 79-6.;2-((5Z)-5-(5-Bromo-2-oxo-1H-indol-3-ylidene)-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl)butanedioic acid
• Target: Bcl-2 Family
• Solubility: Soluble in DMSO
• Storage: Store at -20°C
• IUPAC Name: 2-[5-(5-bromo-2-oxo-1H-indol-3-ylidene)-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]butanedioic acid
• InChI: InChI=1S/C15H9BrN2O6S2/c16-5-1-2-7-6(3-5)10(12(21)17-7)11-13(22)18(15(25)26-11)8(14(23)24)4-9(19)20/h1-3,8H,4H2,(H,17,21)(H,19,20)(H,23,24)
• InChIKey: QGNRETMYLHRUBB-UHFFFAOYSA-N
• SMILES: C1=CC2=C(C=C1Br)C(=C3C(=O)N(C(=S)S3)C(CC(=O)O)C(=O)O)C(=O)N2

CID5721353（Cat No.:I006131）also known as 79-6, is a BCL6 inhibitor with a dissociation constant (Kd) of 138 μM. It specifically targets the B-cell lymphoma 6 (BCL6) protein, which plays a role in the development and progression of certain lymphomas. By inhibiting BCL6, CID5721353 disrupts its function and interferes with the growth and survival of cancer cells. Although it exhibits a relatively moderate affinity for BCL6, further research and optimization may be needed to enhance its potency and efficacy as a therapeutic agent.