Cidofovir dihydrate

• CAT Number: I001840
• CAS Number: 149394-66-1
• Molecular Formula: C8H18N3O8P
• Molecular Weight: 315.22
• Purity: ≥95%
• Target: Cell Cycle/DNA Damage
• Solubility: 10 mM in DMSO
• Storage: Store at -20°C
• Related CAS: 113852-37-2(anhydrous)
• IUPAC Name: [(2S)-1-(4-amino-2-oxopyrimidin-1-yl)-3-hydroxypropan-2-yl]oxymethylphosphonic acid;dihydrate
• InChI: InChI=1S/C8H14N3O6P.2H2O/c9-7-1-2-11(8(13)10-7)3-6(4-12)17-5-18(14,15)16;;/h1-2,6,12H,3-5H2,(H2,9,10,13)(H2,14,15,16);2*1H2/t6-;;/m0../s1
• InChIKey: FPKARFMSZDBYQF-ILKKLZGPSA-N
• SMILES: C1=CN(C(=O)N=C1N)C[C@@H](CO)OCP(=O)(O)O.O.O

Cidofovir dihydrate (Cat No.:I001840) is a potent antiviral medication used primarily for the treatment of cytomegalovirus (CMV) retinitis in immunocompromised patients, such as those with AIDS. It is a nucleotide analog that inhibits viral DNA replication by incorporating into the growing DNA chain and terminating its elongation. Cidofovir dihydrate has also shown activity against other DNA viruses, including herpes simplex viruses (HSV) and human papillomaviruses (HPV). It is typically administered intravenously and may be associated with side effects such as nephrotoxicity. Cidofovir dihydrate is a valuable tool in the management of CMV retinitis and other viral infections in certain patient populations.

Reference

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