Cidofovir diphosphate tri(triethylamine)

• CAT Number: I042846
• Molecular Formula: C26H61N6O12P3
• Molecular Weight: 742.72
• Purity: ≥95%
• Synonyms: [(2S)-1-(4-amino-2-oxopyrimidin-1-yl)-3-hydroxypropan-2-yl]oxymethyl-[hydroxy(phosphonooxy)phosphoryl]oxyphosphinic acid;N,N-diethylethanamine
• InChI: InChI=1S/C8H16N3O12P3.3C6H15N/c9-7-1-2-11(8(13)10-7)3-6(4-12)21-5-24(14,15)22-26(19,20)23-25(16,17)18;3*1-4-7(5-2)6-3/h1-2,6,12H,3-5H2,(H,14,15)(H,19,20)(H2,9,10,13)(H2,16,17,18);3*4-6H2,1-3H3/t6-;;;/m0.../s1
• InChIKey: ACOWIDCBFHAIRH-GSUNZCPGSA-N
• SMILES: CCN(CC)CC.CCN(CC)CC.CCN(CC)CC.C1=CN(C(=O)N=C1N)C[C@@H](CO)OCP(=O)(O)OP(=O)(O)OP(=O)(O)O

Cidofovir diphosphate tri(triethylamine)（Cat No.:I042846）is the active metabolite of cidofovir, an antiviral medication primarily used to treat cytomegalovirus (CMV) infections, particularly in immunocompromised patients, such as those with HIV/AIDS. The diphosphate form is a potent inhibitor of viral DNA polymerase, blocking viral replication. The tri(triethylamine) modification enhances the compound’s solubility and stability in solution, making it more effective in therapeutic applications. Cidofovir diphosphate tri(triethylamine) is also being investigated for its potential to treat other viral infections and as part of antiviral combination therapies.