Cilazaprilat

• CAT Number: R004719
• CAS Number: 90139-06-3
• Molecular Formula: C20H27N3O5
• Molecular Weight: 389.45
• Purity: ≥95%
• Synonyms: (1S,9S)-9-[[(1S)-1-Carboxy-3-phenylpropyl]amino]octahydro-10-oxo-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic Acid; Ro 31-3113
• Storage: -20°C
• IUPAC Name: (4S,7S)-7-[[(1S)-1-carboxy-3-phenylpropyl]amino]-6-oxo-1,2,3,4,7,8,9,10-octahydropyridazino[1,2-a]diazepine-4-carboxylic acid
• InChI: InChI=1S/C20H27N3O5/c24-18-15(8-4-12-22-13-5-9-17(20(27)28)23(18)22)21-16(19(25)26)11-10-14-6-2-1-3-7-14/h1-3,6-7,15-17,21H,4-5,8-13H2,(H,25,26)(H,27,28)/t15-,16-,17-/m0/s1
• InChIKey: UVAUYSRYXACKSC-ULQDDVLXSA-N
• SMILES: C1CC(C(=O)N2C(CCCN2C1)C(=O)O)NC(CCC3=CC=CC=C3)C(=O)O

Cilazaprilat (Cat No.: R004719) is the active metabolite of the ACE inhibitor Cilazapril, essential for advanced cardiovascular research. This compound is crucial for studying the pharmacokinetics, metabolism, and therapeutic effects of ACE inhibitors. Cilazaprilat’s ability to inhibit angiotensin-converting enzyme (ACE) makes it valuable for analyzing mechanisms of blood pressure regulation and heart failure treatment. Cilazaprilat is highly valued for its purity and stability, making it an indispensable tool in developing effective hypertension therapies and cardiovascular disease interventions.