Cilnidipine

• CAT Number: A000275
• CAS Number: 132203-70-4
• Molecular Formula: C27H28N2O7
• Molecular Weight: 492.52
• Purity: ≥95%
• Synonyms: 132203-70-4; Cinalong; Atelec; Siscard; FRC 8653
• Target: Calcium Channel
• Solubility: >24.6mg/mL in DMSO
• Storage: -20°C
• InChI: 1S/C27H28N2O7/c1-18-23(26(30)35-14-8-11-20-9-5-4-6-10-20)25(21-12-7-13-22(17-21)29(32)33)24(19(2)28-18)27(31)36-16-15-34-3/h4-13,17,25,28H,14-16H2,1-3H3/b11-8+
• InChIKey: KJEBULYHNRNJTE-DHZHZOJOSA-N
• SMILES: CC1=C(C(C(=C(N1)C)C(=O)OCC=CC2=CC=CC=C2)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OCCOC

Cilnidipine, also known as FRC-8653, is a calcium channel blocker. Cilnidipine is the novel calcium antagonist accompanied with L-type and N-type calcium channel blocking function. It was approved in 1995. Compared with other calcium antagonists, cilnidipine can act on the N-type calcium channel that existing sympathetic nerve end besides acting on L-type calcium channel that similar to most of the calcium antagonists.

Reference

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