Cimifugin

• CAT Number: I003390
• CAS Number: 37921-38-3
• Molecular Formula: C16H18O6
• Molecular Weight: 306.31
• Purity: ≥95%
• Target: NF-κB
• Solubility: DMSO: ≥ 3 mg/mL
• Storage: Store at -20°C
• IUPAC Name: (2S)-7-(hydroxymethyl)-2-(2-hydroxypropan-2-yl)-4-methoxy-2,3-dihydrofuro[3,2-g]chromen-5-one
• InChI: InChI=1S/C16H18O6/c1-16(2,19)13-5-9-11(22-13)6-12-14(15(9)20-3)10(18)4-8(7-17)21-12/h4,6,13,17,19H,5,7H2,1-3H3/t13-/m0/s1
• InChIKey: ATDBDSBKYKMRGZ-ZDUSSCGKSA-N
• SMILES: CC(C)(C1CC2=C(O1)C=C3C(=C2OC)C(=O)C=C(O3)CO)O

Cimifugin (Cat.No:I003390) is a major components of Yu-ping-feng-san, a Chinese medical formula that is used clinically for allergic diseases and characterized by reducing allergy relapse.

Reference

[1]. Shen D, et al. Screening active components from Yu-ping-feng-san for regulating initiative key factors in allergic sensitization. PLoS One. 2014 Sep 8;9(9):e107279.
[2]. Wang X, et al. Pharmacokinetics of cimifugin in rat plasma after oral administration of the extract of Saposhnikovia divaricatae root. Determination of cimifugin by high performance liquid chromatography coupled with solid phase extraction. Arzneimittelforschung. 2008;58(9):445-50.