Cimpuciclib tosylate

For research use only. Not for therapeutic Use.

  • CAT Number: I042966
  • CAS Number: 2408872-84-2
  • Molecular Formula: C37H43FN8O4S
  • Molecular Weight: 714.85
  • Purity: ≥95%
Inquiry Now

Cimpuciclib tosylate(Cat No.:I042966)is an investigational small molecule inhibitor targeting cyclin-dependent kinase 9 (CDK9), an enzyme involved in regulating transcriptional elongation and RNA synthesis. By inhibiting CDK9, Cimpuciclib tosylate interferes with the transcription of genes essential for cancer cell survival, leading to cell cycle arrest and apoptosis in rapidly proliferating tumor cells. It is being studied for its potential as an anticancer agent, particularly in the treatment of hematologic cancers and solid tumors. Ongoing research is focused on evaluating its safety, efficacy, pharmacokinetics, and its role in combination therapies.


CAS Number 2408872-84-2
Synonyms

[4-(cyclopropylamino)piperidin-1-yl]-[6-[[5-fluoro-4-(2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-yl]amino]-2-methylpyridin-3-yl]methanone;4-methylbenzenesulfonic acid

Molecular Formula C37H43FN8O4S
Purity ≥95%
IUPAC Name [4-(cyclopropylamino)piperidin-1-yl]-[6-[[5-fluoro-4-(2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-yl]amino]-2-methylpyridin-3-yl]methanone;4-methylbenzenesulfonic acid
InChI InChI=1S/C30H35FN8O.C7H8O3S/c1-17(2)39-19(4)34-25-9-5-20(15-26(25)39)28-24(31)16-32-30(37-28)36-27-10-8-23(18(3)33-27)29(40)38-13-11-22(12-14-38)35-21-6-7-21;1-6-2-4-7(5-3-6)11(8,9)10/h5,8-10,15-17,21-22,35H,6-7,11-14H2,1-4H3,(H,32,33,36,37);2-5H,1H3,(H,8,9,10)
InChIKey GHPZVWMOCAVFLC-UHFFFAOYSA-N
SMILES CC1=CC=C(C=C1)S(=O)(=O)O.CC1=C(C=CC(=N1)NC2=NC=C(C(=N2)C3=CC4=C(C=C3)N=C(N4C(C)C)C)F)C(=O)N5CCC(CC5)NC6CC6

Request a Quote