Cinacalcet metabolite M4

For research use only. Not for therapeutic Use.

  • CAT Number: M010464
  • CAS Number: 104774-87-0
  • Molecular Formula: C10H12F3N
  • Molecular Weight: 203.20
  • Purity: ≥95%
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Cinacalcet metabolite M4 is a metabolite of Cinacalcet. Cinacalcet is an orally active, allosteric agonist of Ca receptor (CaR), used for cardiovascular disease[1][2].


Catalog Number M010464
CAS Number 104774-87-0
Synonyms

3-[3-(trifluoromethyl)phenyl]propan-1-amine

Molecular Formula C10H12F3N
Purity ≥95%
InChI InChI=1S/C10H12F3N/c11-10(12,13)9-5-1-3-8(7-9)4-2-6-14/h1,3,5,7H,2,4,6,14H2
InChIKey JMTLMFBJIQWJPW-UHFFFAOYSA-N
SMILES C1=CC(=CC(=C1)C(F)(F)F)CCCN
Reference

[1]. Kumar GN, et al. Metabolism and disposition of calcimimetic agent cinacalcet HCl in humans and animalmodels. Drug Metab Dispos. 2004 Dec;32(12):1491-500.
 [Content Brief]

[2]. Bushinsky DA, et al. Effect of cinacalcet on urine calcium excretion and supersaturation in genetic hypercalciuric stone-forming rats. Kidney Int. 2006 May;69(9):1586-92.
 [Content Brief]

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