Cinnabarinic Acid

  • CAT Number: R011057
  • CAS Number: 606-59-7
  • Molecular Formula: C14H8N2O6
  • Molecular Weight: 300.22
  • Purity: ≥95%
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Cinnabarinic acid(Cat No.:R011057) is an endogenous metabolite produced by the tryptophan kynurenine pathway. It acts as a specific allosteric agonist for the metabotropic glutamate receptor subtype 4 (mGlu4) and selectively interacts with the glutamate-binding pocket residues of mGlu4, with no activity on other mGlu receptor subtypes. Cinnabarinic acid’s ability to induce apoptosis makes it a valuable compound in research related to neuronal cell death and potential therapeutic applications for neurological disorders. Its specific interaction with mGlu4 receptors holds promise for targeted drug development in neurodegenerative diseases.


Catalog Number R011057
CAS Number 606-59-7
Synonyms

2-Amino-3-oxo-3H-phenoxazine-1,9-dicarboxylic Acid; Cinnabaric Acid;

Molecular Formula C14H8N2O6
Purity ≥95%
Target GluR
Solubility Soluble in DMSO > 10 mM
Storage Store at 2-8°C
IUPAC Name 2-amino-3-oxophenoxazine-1,9-dicarboxylic acid
InChI InChI=1S/C14H8N2O6/c15-10-6(17)4-8-12(9(10)14(20)21)16-11-5(13(18)19)2-1-3-7(11)22-8/h1-4H,15H2,(H,18,19)(H,20,21)
InChIKey FSBKJYLVDRVPTK-UHFFFAOYSA-N
SMILES C1=CC(=C2C(=C1)OC3=CC(=O)C(=C(C3=N2)C(=O)O)N)C(=O)O

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