Cinnarizine-d8

• CAT Number: S000384
• CAS Number: 1185242-27-6
• Molecular Formula: C26H20D8N2
• Molecular Weight: 376.56
• Purity: ≥95%
• IUPAC Name: 1-benzhydryl-2,2,3,3,5,5,6,6-octadeuterio-4-[(E)-3-phenylprop-2-enyl]piperazine
• InChI: InChI=1S/C26H28N2/c1-4-11-23(12-5-1)13-10-18-27-19-21-28(22-20-27)26(24-14-6-2-7-15-24)25-16-8-3-9-17-25/h1-17,26H,18-22H2/b13-10+/i19D2,20D2,21D2,22D2
• InChIKey: DERZBLKQOCDDDZ-RVEWZOGKSA-N
• SMILES: C1CN(CCN1CC=CC2=CC=CC=C2)C(C3=CC=CC=C3)C4=CC=CC=C4

Cinnarizine-d8（Cat No.:S000384） is a deuterated version of cinnarizine, where eight hydrogen atoms are replaced with deuterium. This modification improves the drug’s stability and is used for detailed pharmacokinetic and metabolic studies. Cinnarizine is an antihistamine and calcium channel blocker commonly used to treat nausea, vomiting, and dizziness associated with motion sickness, and also for the management of peripheral circulatory disorders. It works by blocking calcium channels and histamine H1 receptors. The deuterated version, Cinnarizine-d8, allows researchers to more accurately study the drug’s absorption, distribution, metabolism, and excretion, enhancing understanding of its therapeutic effects.