Cinobufagin

• CAT Number: I003629
• CAS Number: 470-37-1
• Molecular Formula: C26H34O6
• Molecular Weight: 442.54
• Purity: ≥95%
• Target: Apoptosis
• Solubility: DMSO: 43 mg/mL
• Storage: Store at -20℃
• IUPAC Name: [(1R,2S,4R,5R,6R,7R,10S,11S,14S,16R)-14-hydroxy-7,11-dimethyl-6-(6-oxopyran-3-yl)-3-oxapentacyclo[8.8.0.02,4.02,7.011,16]octadecan-5-yl] acetate
• InChI: InChI=1S/C26H34O6/c1-14(27)31-22-21(15-4-7-20(29)30-13-15)25(3)11-9-18-19(26(25)23(22)32-26)6-5-16-12-17(28)8-10-24(16,18)2/h4,7,13,16-19,21-23,28H,5-6,8-12H2,1-3H3/t16-,17+,18+,19-,21+,22-,23-,24+,25-,26-/m1/s1
• InChIKey: SCULJPGYOQQXTK-OLRINKBESA-N
• SMILES: CC(=O)O[C@@H]1[C@@H]([C@]2(CC[C@H]3[C@H]([C@@]24[C@@H]1O4)CC[C@H]5[C@@]3(CC[C@@H](C5)O)C)C)C6=COC(=O)C=C6

Cinobufagin (Cat No.:I003629 ) is a natural cardiac glycoside found in the skin of the Chinese giant toad (Bufo bufo gargarizans). It has shown potential pharmacological effects, including anti-cancer, anti-inflammatory, and anti-arrhythmic properties. Cinobufagin works by inhibiting the Na+/K+-ATPase pump, which can influence cellular ion balance and has been studied for its potential in treating certain types of cancer and heart diseases. Despite its promising effects, its use is limited by toxicity, and more research is needed to evaluate safety and efficacy.