Ciprofloxacin-d8

• CAT Number: R006134
• CAS Number: 1130050-35-9
• Molecular Formula: C17H18FN3O3
• Molecular Weight: 339.396
• Purity: ≥95%
• Synonyms: 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl-d8)-3-quinolinecarboxylic Acid; Bay q 3939-d8; Ciflafin-d8; Ciprine-d8; Cipro IV-d8; Ciprobay 100-d8; Ciprofloxacillin-d8
• Target: Bacterial
• Storage: 2°C to 8°C
• Related CAS: 85721-33-1 (unlabeled)
• IUPAC Name: 1-cyclopropyl-6-fluoro-7-(2,2,3,3,5,5,6,6-octadeuteriopiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
• InChI: InChI=1S/C17H18FN3O3/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24/h7-10,19H,1-6H2,(H,23,24)/i3D2,4D2,5D2,6D2
• InChIKey: MYSWGUAQZAJSOK-SQUIKQQTSA-N
• SMILES: C1CC1N2C=C(C(=O)C3=CC(=C(C=C32)N4CCNCC4)F)C(=O)O

Ciprofloxacin-d8(CAT: R006134) is a deuterium-labeled derivative of ciprofloxacin, a fluoroquinolone antibiotic. Its mode of action involves inhibiting bacterial DNA gyrase and topoisomerase IV enzymes, disrupting DNA replication and repair in bacteria. Pharmacologically, Ciprofloxacin-d8 retains the antibacterial properties of ciprofloxacin but incorporates deuterium isotopes for use as a tracer in pharmacokinetic studies or other analytical applications. Ciprofloxacin-d8 is utilized to track the absorption, distribution, metabolism, and excretion of ciprofloxacin in biological systems, providing valuable insights into drug disposition and interactions. Its incorporation into studies enhances our understanding of ciprofloxacin’s pharmacokinetics and contributes to refining dosing regimens and optimizing drug therapies.