For research use only. Not for therapeutic Use.
cis-1-Hydroxy-2,7-diamino Mitosene(CAT: C000226) is a compound derived from Mitomycin C, an antitumor antibiotic widely used in cancer chemotherapy. This derivative is characterized by the addition of a hydroxy group and amino groups to the Mitosene structure, enhancing its antineoplastic properties. Mitomycin C and its derivatives are known for their ability to cross-link DNA strands, inhibiting DNA replication and RNA synthesis in rapidly dividing cancer cells.
| Catalog Number | C000226 |
| CAS Number | 98462-75-0 |
| Synonyms | (1S,2S)-2,7-Diamino-9-[[(aminocarbonyl)oxy]methyl]-2,3-dihydro-1-hydroxy-6-methyl-1H-pyrrolo[1,2-a]indole-5,8-dione; (1S-cis)-2,7-Diamino-9-[[(aminocarbonyl)oxy]methyl]-2,3-dihydro-1-hydroxy-6-methyl-1H-Pyrrolo[1,2-a]indole-5,8-dione; |
| Molecular Formula | C₁₄H₁₆N₄O₅ |
| Purity | ≥95% |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Appearance | Red to Very Dark Purple Solid |
| Storage | - 86°C, Inert atmosphere, Light sensitive |
| Reference | Kinoshita, S., et al.: J. Med. Chem., 14, 13 (1971); Beijnen, J.H., et al.: Anal. Profiles Drug Subs., 16, 361 (1986); Paz, M. M.: Bioorg. Med. Chem. Lett., 20, 31-34 (2010) |
