cis-[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-4-yl-methyl)-1,3-dioxolan-4-yl]methyl Methanesulfonate

• CAT Number: C000638
• CAS Number: 103661-14-9
• Molecular Formula: C₁₄H₁₅Cl₂N₃O₅S
• Molecular Weight: 408.26
• Purity: ≥95%
• Synonyms: Itraconazole Impurity 16
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• Appearance: Pale Brown to Light Brown Solid
• Storage: -20°C

cis-[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-4-yl-methyl)-1,3-dioxolan-4-yl]methyl Methanesulfonate (Itraconazole Impurity 16) is an impurity in the synthesis of Itraconazole , an orally active antimycotic structurally related to Ketoconazole. Antifungal.

Reference

Espinel-Ingroff, A., et al.: Antimicrob. Agents Chemother., 26, 5 (1984), Heykants, J., et al.: Mycoses, 32, Suppl 1, 67 (1989);