cis-4-Hydroxy-lomustine-d10

• CAT Number: R029947
• CAS Number: NA
• Molecular Formula: C₉H₇D₉ClN₃O₃
• Molecular Weight: 258.75
• Purity: ≥95%
• Synonyms: 1-(2-Chloroethyl)-3-(cis-4-hydroxycyclohexyl)-1-nitrosourea-d10; N-(2-Chloroethyl)-N’-(cis-4-hydroxycyclohexyl)-N-nitrosourea-d10; NSC 239724-d10; cis-4-Hydroxy CCNU-d10
• Storage: -20°C
• IUPAC Name: 1-(2-chloroethyl)-1-nitroso-3-[(1S,4R)-1,2,2,3,3,4,5,6,6-nonadeuterio-4-hydroxycyclohexyl]urea
• InChI: InChI=1S/C9H16ClN3O3/c10-5-6-13(12-16)9(15)11-7-1-3-8(14)4-2-7/h7-8,14H,1-6H2,(H,11,15)/t7-,8+/i1D2,2D2,3D,4D2,7D,8D/t3?,7-,8+/m0/s1
• InChIKey: BTNKSMIZKSHDNT-GXBUCOOCSA-N
• SMILES: C1CC(CCC1NC(=O)N(CCCl)N=O)O

cis-4-Hydroxy-lomustine-d10（Cat No.:R029947） is a deuterated version of cis-4-Hydroxy-lomustine, where ten hydrogen atoms are replaced with deuterium. This isotopic modification significantly enhances the molecule’s stability and is particularly useful for detailed pharmacokinetic and metabolic research. cis-4-Hydroxy-lomustine is an active metabolite of lomustine, a chemotherapy drug used to treat various cancers, including brain tumors and Hodgkin’s lymphoma. The deuterated variant provides clearer insights into the drug’s metabolic pathways and mechanisms of action, allowing for more precise tracking and analysis of its behavior and effects within the body, and facilitating the development of more effective cancer treatments.