cis-4-Hydroxy-lomustine

• CAT Number: R029946
• CAS Number: 52049-26-0
• Molecular Formula: C9H16ClN3O3
• Molecular Weight: 249.695
• Purity: ≥95%
• Synonyms: 1-(2-Chloroethyl)-3-(cis-4-hydroxycyclohexyl)-1-nitrosourea; N-(2-Chloroethyl)-N’-(cis-4-hydroxycyclohexyl)-N-nitrosourea; NSC 239724; cis-4-Hydroxy CCNU
• Storage: -20°C
• IUPAC Name: 1-(2-chloroethyl)-3-(4-hydroxycyclohexyl)-1-nitrosourea
• InChI: InChI=1S/C9H16ClN3O3/c10-5-6-13(12-16)9(15)11-7-1-3-8(14)4-2-7/h7-8,14H,1-6H2,(H,11,15)
• InChIKey: BTNKSMIZKSHDNT-UHFFFAOYSA-N
• SMILES: C1CC(CCC1NC(=O)N(CCCl)N=O)O

Cis-4-Hydroxy-lomustine is a derivative of the chemotherapy drug lomustine, used in cancer treatment. This compound specifically targets and interferes with DNA synthesis in cancer cells, enhancing its effectiveness. Research focuses on its potential to improve therapeutic outcomes in brain tumors and other malignancies. Its unique cis-configuration contributes to its enhanced pharmacological properties and cancer-fighting capabilities.