cis-Clopidogrel-MP Derivative

• CAT Number: I014040
• CAS Number: 1122047-98-6
• Molecular Formula: C₂₅H₂₆ClNO₆S
• Molecular Weight: 504
• Purity: ≥95%
• Target: Drug Metabolite
• Storage: Store at -20°C
• IUPAC Name: (2Z)-2-[1-[1-(2-chlorophenyl)-2-methoxy-2-oxoethyl]-4-[2-(3-methoxyphenyl)-2-oxoethyl]sulfanylpiperidin-3-ylidene]acetic acid
• InChI: InChI=1S/C25H26ClNO6S/c1-32-18-7-5-6-16(12-18)21(28)15-34-22-10-11-27(14-17(22)13-23(29)30)24(25(31)33-2)19-8-3-4-9-20(19)26/h3-9,12-13,22,24H,10-11,14-15H2,1-2H3,(H,29,30)/b17-13-
• InChIKey: FNCOEMFSIDGTAR-LGMDPLHJSA-N
• SMILES: COC1=CC=CC(=C1)C(=O)CSC2CCN(CC2=CC(=O)O)C(C3=CC=CC=C3Cl)C(=O)OC

cis-Clopidogrel-MP Derivative (Cas No.:1122047-98-6) is a derivative of the active metabolite of Clopidogrel, a well-known orally active platelet inhibitor. Clopidogrel exerts its antiplatelet effects by targeting the P2Y12 receptor, thereby inhibiting platelet activation and aggregation. The cis-Clopidogrel-MP Derivative, specifically the 3′-methoxy acetophenone derivative, is likely designed to enhance the pharmacological properties or modify the drug delivery of Clopidogrel.

Reference

[1]. Makoto Takahashi, et al. Quantitative determination of clopidogrel active metabolite in human plasma by LC-MS/MS. harm Biomed Anal. 2008 Dec 1;48(4):1219-24.[2]. Zongyu Zheng, et al. Clopidogrel Reduces Fibronectin Accumulation and Improves Diabetes-Induced Renal Fibrosis. Int J Biol Sci. 2019 Jan.