cis-Piperidine-2,3-dicarboxylic acid

• CAT Number: I024810
• CAS Number: 46026-75-9
• Molecular Formula: C7H11NO4
• Molecular Weight: 173.17
• Purity: ≥95%
• Synonyms: (2S,3R)-piperidine-2,3-dicarboxylic acid
• InChI: InChI=1S/C7H11NO4/c9-6(10)4-2-1-3-8-5(4)7(11)12/h4-5,8H,1-3H2,(H,9,10)(H,11,12)/t4-,5+/m1/s1
• InChIKey: PTLWNCBCBZZBJI-UHNVWZDZSA-N
• SMILES: C1CC(C(NC1)C(=O)O)C(=O)O

cis-Piperidine-2,3-dicarboxylic acid(CAT: I024810) is a cyclic dicarboxylic acid compound and structural analog of glutamate. It is known to act as an antagonist of ionotropic glutamate receptors, particularly the NMDA and AMPA/kainate subtypes, making it a useful research tool in neuroscience and pharmacology. By inhibiting excitatory neurotransmission, cis-piperidine-2,3-dicarboxylic acid helps in studying the roles of glutamate signaling in synaptic plasticity, excitotoxicity, and neurodegenerative diseases. Its ability to modulate glutamatergic pathways highlights its value in the development of potential therapies for epilepsy, ischemia, and other CNS disorders linked to excessive excitatory activity.