For research use only. Not for therapeutic Use.
Cisplatin(Cat No.:A000881)is a powerful chemotherapy drug widely used to treat various cancers, including testicular, ovarian, bladder, and lung cancers. It works by binding to DNA in cancer cells, causing crosslinking and preventing cell division, leading to cell death. Cisplatin’s efficacy in shrinking tumors and improving survival rates has made it a cornerstone in oncology. Despite its effectiveness, Cisplatin can cause side effects such as nephrotoxicity, ototoxicity, and neurotoxicity. Ongoing research aims to enhance its therapeutic index and reduce adverse effects, making Cisplatin a crucial component of cancer treatment regimens.
Catalog Number | A000881 |
CAS Number | 15663-27-1 |
Synonyms | Cisplatin |
Molecular Formula | Cl2H6N2Pt |
Purity | ≥95% |
Target | Caspase |
Solubility | >15mg/mL in DMSO |
IUPAC Name | azanide;dichloroplatinum(2+) |
InChI | InChI=1S/2ClH.2H2N.Pt/h2*1H;2*1H2;/q;;2*-1;+4/p-2 |
InChIKey | DQLATGHUWYMOKM-UHFFFAOYSA-L |
SMILES | [NH2-].[NH2-].Cl[Pt+2]Cl |