For research use only. Not for therapeutic Use.
<p style=/line-height:25px/>Citalopram hydrobromide (Cat.No:I004240) is an antidepressant drug of the selective serotonin reuptake inhibitor (SSRI) class. It has US FDA approval to treat major depression.</p>
| Catalog Number | I004240 |
| CAS Number | 59729-32-7 |
| Synonyms | Bonitrile;Lu 10-171B;Nitalapram;Prepram |
| Molecular Formula | C20H21FN2O • HBr |
| Purity | ≥95% |
| Target | Selective Serotonin Reuptake Inhibitor |
| Solubility | DMSO:38mg/mL |
| Storage | Store at -20°C |
| IUPAC Name | 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-carbonitrile;hydrobromide |
| InChI | InChI=1S/C20H21FN2O.BrH/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20;/h4-9,12H,3,10-11,14H2,1-2H3;1H |
| InChIKey | WSEQXVZVJXJVFP-UHFFFAOYSA-N |
| SMILES | CN(C)CCCC1(C2=CC=C(F)C=C2)OCC3=CC(C#N)=CC=C31 |
| Reference | </br>1:Utility of eosin Y as a complexing reagent for the determination of citalopram hydrobromide in commercial dosage forms by fluorescence spectrophotometry. Azmi SN, Al-Fazari A, Al-Badaei M, Al-Mahrazi R.Luminescence. 2015 Dec;30(8):1352-9. doi: 10.1002/bio.2905. Epub 2015 Mar 31. PMID: 25829234 </br>2:Spectrophotometric determination of citalopram hydrobromide in tablet dosage form using chloranil. Raza A, Ansari TM.Pak J Pharm Sci. 2014 Mar;27(2):255-60. PMID: 24577911 </br>3:Development and application of spectrophotometric methods for the determination of citalopram hydrobromide in dosage forms. Raza A.Chem Pharm Bull (Tokyo). 2006 Apr;54(4):432-4. PMID: 16595940 Free Article</br>4:The effect of citalopram hydrobromide on 5-HT2A receptors in the impulsive-aggressive dog, as measured with 123I-5-I-R91150 SPECT. Peremans K, Audenaert K, Hoybergs Y, Otte A, Goethals I, Gielen I, Blankaert P, Vervaet M, van Heeringen C, Dierckx R.Eur J Nucl Med Mol Imaging. 2005 Jun;32(6):708-16. PMID: 15739093 |
