For research use only. Not for therapeutic Use.
CITFA is a selective GPER agonist with an EC50 value of 38.7 nM. CITFA significantly increased axonal and dendritic growth in neurons extracted from embryonic day 18 (E18) fetal rat hippocampal neurons.
KEYWORDS: CITFA | Supplier | GPER agonist | CAS [2379989-52-1] | Estrogen | GPER | Agonist | Receptors | G protein-coupled estrogen receptor | GPR30
| Catalog Number | I047701 |
| CAS Number | 2379989-52-1 |
| Molecular Formula | C25H35NO2 |
| Purity | ≥95% |
| IUPAC Name | 2-cyclohexyl-N-[[5-(oxan-2-yl)furan-2-yl]methyl]-4-propan-2-ylaniline |
| InChI | InChI=1S/C25H35NO2/c1-18(2)20-11-13-23(22(16-20)19-8-4-3-5-9-19)26-17-21-12-14-25(28-21)24-10-6-7-15-27-24/h11-14,16,18-19,24,26H,3-10,15,17H2,1-2H3 |
| SMILES | CC(C)C1=CC(=C(C=C1)NCC2=CC=C(O2)C3CCCCO3)C4CCCCC4 |
| Reference | C DeLeon et al. Novel GPER Agonist, CITFA, Increases Neurite Growth in Rat Embryonic (E18) Hippocampal Neurons. ACS Chem Neurosci. 2022 Apr 20;13(8):1119-1128. |
