Citreoviridin (80%, Contain Isocitreoviridin)

• CAT Number: R062402
• CAS Number: 25425-12-1
• Molecular Formula: C23H30O6
• Molecular Weight: 402.5
• Purity: ≥95%
• Synonyms: Citreoviridin A; Citreoviridine; Citreoviridine A; 5-Hydroxy-3-methoxy-4,12-dimethyl-13-(tetrahydro-3,4-dihydroxy-2,4,5-trimethyl-2-furyl)-2,4,6,8,10,12-tridecahexaenoic Acid, δ-Lactone; [2S-[2α(1E,3E,5E,7E),3β,4α,5α]]-4-Methoxy-5-methyl-6-[7-methyl-
• Appearance: Yellow powder
• Storage: -20°C
• IUPAC Name: 6-[(1E,3E,5E,7E)-8-[(2S,3R,4R,5R)-3,4-dihydroxy-2,4,5-trimethyloxolan-2-yl]-7-methylocta-1,3,5,7-tetraenyl]-4-methoxy-5-methylpyran-2-one
• InChI: InChI=1S/C23H30O6/c1-15(14-22(4)21(25)23(5,26)17(3)29-22)11-9-7-8-10-12-18-16(2)19(27-6)13-20(24)28-18/h7-14,17,21,25-26H,1-6H3/b8-7+,11-9+,12-10+,15-14+/t17-,21+,22+,23+/m1/s1
• InChIKey: JLSVDPQAIKFBTO-OMCRQDLASA-N
• SMILES: CC1C(C(C(O1)(C)C=C(C)C=CC=CC=CC2=C(C(=CC(=O)O2)OC)C)O)(C)O

Citreoviridin(CAS 25425-12-1) is a neurotoxic mycotoxin from Penicillium citeoviride, Penicillium toxicarium, Penicillium ochrosalmoneum, Penicillium ochrosalmoneum, Aspergillus terreus, and several other related fungi. Citreoviridin is believed to be the cause of the Acute Cardiac Beri-Beri disease. Naturally, It is formed on rice improperly stored.

Reference

1.Citreoviridins from Aspergillus terreus. Franck B. & Gehrken H-P. Angew. Chem. Int. Ed. Engl. 1980, 19, 461. 

2.Isolation of citreoviridin from Penicillium charlesii cultures and molded pecan fragments. Cole R. J. et al. Appl. Environ. Microbiol. 1981, 42, 677. 

3.Citreoviridin, a specific inhibitor of the mitochondrial adenosine triphosphatase. Linnett P. E. et al. Biochem. J. 1978, 170, 503. 

4.Interaction of Escherichia coli adenosine triphosphatase with aurovertin and citreoviridin: inhibition and fluorescence studies. Satre M. et al. J. Bacteriol. 1980, 142, 768. 

5.Binding of citreoviridin to the beta subunit of the yeast F1-ATPase. Gause E. M. et al. J. Biol. Chem.1981, 256, 557.