CJ-2360

• CAT Number: I024838
• CAS Number: 2226742-61-4
• Molecular Formula: C27H30FN5O2
• Molecular Weight: 475.57
• Purity: 98%
• Synonyms: CJ-2360; CJ2360; CJ 2360
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 4-fluoro-2-methoxy-11-oxo-5-propan-2-yl-3-[(3R,5S)-3,4,5-trimethylpiperazin-1-yl]-6H-indolo[2,3-b]quinoline-8-carbonitrile
• InChI: InChI=1S/C27H30FN5O2/c1-14(2)33-24-19(26(34)22-18-8-7-17(11-29)9-20(18)30-27(22)33)10-21(35-6)25(23(24)28)32-12-15(3)31(5)16(4)13-32/h7-10,14-16,30H,12-13H2,1-6H3/t15-,16+ Create Date: 2018-06-23
• InChIKey: LOONVQWRKJLEEG-IYBDPMFKSA-N
• SMILES: C[C@@H]1CN(C[C@@H](N1C)C)C2=C(C=C3C(=C2F)N(C4=C(C3=O)C5=C(N4)C=C(C=C5)C#N)C(C)C)OC

CJ-2360（Cat No.:I024838）is a selective inhibitor of the enzyme histone deacetylase 6 (HDAC6), which plays a significant role in regulating protein degradation, cellular stress responses, and microtubule dynamics. By inhibiting HDAC6, CJ-2360 promotes the acetylation of tubulin and other substrates, which can lead to the disruption of cancer cell growth and metastasis. This compound is primarily studied for its potential anticancer properties, particularly in cancers where HDAC6 is overexpressed. In addition to oncology, CJ-2360 may have applications in neurodegenerative diseases due to its effects on protein aggregation and cellular stress mechanisms.