CK2-IN-3b

• CAT Number: I012714
• CAS Number: 1361229-76-6
• Molecular Formula: C18H14N2O4S
• Molecular Weight: 354.38
• Purity: ≥95%
• Synonyms: 4-(2-(4-Methoxybenzamido)thiazol-5-yl)benzoic acid
• IUPAC Name: 4-[2-[(4-methoxybenzoyl)amino]-1,3-thiazol-5-yl]benzoic acid
• InChI: InChI=1S/C18H14N2O4S/c1-24-14-8-6-12(7-9-14)16(21)20-18-19-10-15(25-18)11-2-4-13(5-3-11)17(22)23/h2-10H,1H3,(H,22,23)(H,19,20,21)
• InChIKey: UPIVZLFKYMNZDG-UHFFFAOYSA-N
• SMILES: COC1=CC=C(C=C1)C(=O)NC2=NC=C(S2)C3=CC=C(C=C3)C(=O)O

CK2-IN-3b (CAT: I012714) is a potent and selective inhibitor of protein kinase CK2 (casein kinase 2), a serine/threonine kinase involved in regulating various cellular processes, including cell growth, proliferation, and survival. CK2-IN-3b specifically targets the ATP-binding site of CK2 and inhibits its kinase activity. By blocking CK2 activity, CK2-IN-3b can modulate signaling pathways and interfere with the phosphorylation of downstream targets. This compound has shown potential in preclinical studies for the treatment of cancer and other diseases where dysregulation of CK2 activity is implicated.