CK2/ERK8-IN-1

• CAT Number: I016195
• CAS Number: 1085822-09-8
• Molecular Formula: C₁₁H₉Br₄N₃O₂
• Molecular Weight: 534.82
• Purity: ≥95%
• IUPAC Name: 2-[4,5,6,7-tetrabromo-2-(dimethylamino)benzimidazol-1-yl]acetic acid
• InChI: InChI=1S/C11H9Br4N3O2/c1-17(2)11-16-9-7(14)5(12)6(13)8(15)10(9)18(11)3-4(19)20/h3H2,1-2H3,(H,19,20)
• InChIKey: PHAOTASRLQMKBE-UHFFFAOYSA-N
• SMILES: CN(C)C1=NC2=C(N1CC(=O)O)C(=C(C(=C2Br)Br)Br)Br

CK2/ERK8-IN-1(Cat No.:I016195) is a compound that acts as an inhibitor of both CK2 (casein kinase 2) and ERK8 (extracellular signal-regulated kinase 8). CK2 is a protein kinase involved in various cellular processes, including cell growth and proliferation, while ERK8 is a member of the MAPK (mitogen-activated protein kinase) family implicated in cell signaling pathways. By inhibiting the activity of CK2 and ERK8, this compound has the potential to modulate these signaling pathways and impact cellular functions. Further studies are required to explore its specific effects and potential therapeutic applications.

Reference

[1]. Pagano MA, et al. The selectivity of inhibitors of protein kinase CK2: an update. Biochem J. 2008 Nov 1;415(3):353-65.