For research use only. Not for therapeutic Use.
A dopamine transporter inhibitor and a 5-HT inhibitor potentially for the treatment of depression.
| Catalog Number | I006155 |
| CAS Number | 86215-36-3 |
| Synonyms | CL-216303; DOV-216303; CL216303; DOV216303; CL 216303; DOV 216303;3-Azabicyclo(3.1.0)hexane, 1-(3,4-dichlorophenyl)-, hydrochloride (1:1) |
| Molecular Formula | C11H12Cl3N |
| Purity | ≥95% |
| Target | Dopamine Transporter |
| Solubility | Soluble in DMSO |
| Storage | 0 - 4°C for short term ,or -20 °C for long term |
| IUPAC Name | 1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane;hydrochloride |
| InChI | InChI=1S/C11H11Cl2N.ClH/c12-9-2-1-7(3-10(9)13)11-4-8(11)5-14-6-11;/h1-3,8,14H,4-6H2;1H |
| InChIKey | KAGBHVBIOJBGBD-UHFFFAOYSA-N |
| SMILES | C1C2C1(CNC2)C3=CC(=C(C=C3)Cl)Cl.Cl |
| Reference | </br>1:Effects of Clove Oil and Lidocaine-HCl Anesthesia on Water Parameter during Simulated Transportation in the Marine Medaka, <i>Oryzias dancena</i>. Park IS, Gil HW, Lee TH, Nam YK, Lim SG, Kim DS.Dev Reprod. 2017 Mar;21(1):19-33. doi: 10.12717/DR.2017.21.1.019. Epub 2017 Mar 31. PMID: 28484741 Free PMC Article</br>2:Olive (Olea europaea) leaf methanolic extract prevents HCl/ethanol-induced gastritis in rats by attenuating inflammation and augmenting antioxidant enzyme activities. Al-Quraishy S, Othman MS, Dkhil MA, Abdel Moneim AE.Biomed Pharmacother. 2017 Apr 29;91:338-349. doi: 10.1016/j.biopha.2017.04.069. [Epub ahead of print] PMID: 28463797 </br>3:HCl dissociating on a rigid Au(111) surface: A six-dimensional quantum mechanical study on a new potential energy surface based on the RPBE functional. Liu T, Fu B, Zhang DH.J Chem Phys. 2017 Apr 28;146(16):164706. doi: 10.1063/1.4982051. PMID: 28456190 </br>4:A new ab initio potential energy surface of LiClH (1A/’) system and quantum dynamics calculation for Li + HCl (v = 0, j = 0-2) → LiCl + H reaction. Tan RS, Zhai HC, Yan W, Gao F, Lin SY.J Chem Phys. 2017 Apr 28;146(16):164305. doi: 10.1063/1.4982066. PMID: 28456188 </br>5:Spectroscopic Characterization of the Reaction Products between the Criegee Intermediate CH<sub>2</sub> OO and HCl. Cabezas C, Endo Y.Chemphyschem. 2017 Apr 27. doi: 10.1002/cphc.201700446. [Epub ahead of print] PMID: 28449411 </br>6:Formulation, release characteristics, and bioavailability study of gastroretentive floating matrix tablet and floating raft system of Mebeverine HCl. El Nabarawi MA, Teaima MH, Abd El-Monem RA, El Nabarawy NA, Gaber DA.Drug Des Devel Ther. 2017 Apr 3;11:1081-1093. doi: 10.2147/DDDT.S131936. eCollection 2017. PMID: 28435220 Free PMC Article</br>7:Lipids bearing extruded-spheronized pellets for extended release of poorly soluble antiemetic agent-Meclizine HCl. Qazi F, Shoaib MH, Yousuf RI, Nasiri MI, Ahmed K, Ahmad M.Lipids Health Dis. 2017 Apr 12;16(1):75. doi: 10.1186/s12944-017-0466-x. PMID: 28403892 Free PMC Article</br>8:Acute exposure of primary rat soleus muscle to zilpaterol HCl (β2 adrenergic agonist), TNFα, or IL-6 in culture increases glucose oxidation rates independent of the impact on insulin signaling or glucose uptake. Cadaret CN, Beede KA, Riley HE, Yates DT.Cytokine. 2017 Apr 5;96:107-113. doi: 10.1016/j.cyto.2017.03.014. [Epub ahead of print] PMID: 28390265 </br>9:Effects of anabolic implants and ractopamine-HCl on muscle fiber morphometrics, collagen solubility, and tenderness of beef longissimus lumborum steaks. Ebarb SM, Phelps KJ, Drouillard JS, Maddock-Carlin KR, Vaughn MA, Burnett DD, Noel JA, Van Bibber-Krueger CL, Paulk CB, Grieger DM, Gonzalez JM.J Anim Sci. 2017 Mar;95(3):1219-1231. doi: 10.2527/jas.2016.1263. PMID: 28380530 </br>10:Comparative plasma and tissue distribution of Sun Pharma/’s generic doxorubicin HCl liposome injection versus Caelyx<sup>®</sup> (doxorubicin HCl liposome injection) in syngeneic fibrosarcoma-bearing BALB/c mice and Sprague-Dawley rats. Burade V, Bhowmick S, Maiti K, Zalawadia R, Jain D, Rajamannar T.Cancer Chemother Pharmacol. 2017 May;79(5):899-913. doi: 10.1007/s00280-017-3278-9. Epub 2017 Mar 27. PMID: 28349166 Free PMC Article |
