For research use only. Not for therapeutic Use.
Cl-4AS-1 (CAT: I010825) is a potent steroidal androgen receptor agonist with an IC50 value of 12 nM. It acts by mimicking the action of 5α-dihydrotestosterone (DHT), a natural androgen hormone. As an androgen receptor agonist, Cl-4AS-1 binds to and activates the androgen receptor, resulting in various androgenic effects. These effects can include the promotion of muscle growth, the development and maintenance of male sexual characteristics, and the regulation of various physiological processes. Cl-4AS-1’s strong binding affinity for the androgen receptor makes it a potent agonist in modulating androgen receptor-mediated signaling pathways.
| Catalog Number | I010825 |
| CAS Number | 188589-66-4 |
| Synonyms | (4aα,4bβ,6aα,7α,9aβ,9bα,11aβ)-N-(2-Chlorophenyl)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1,4,6a-trimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxamide |
| Molecular Formula | C26H33ClN2O2 |
| Purity | ≥95% |
| Target | Androgen Receptor |
| Solubility | Soluble to 10 mM in DMSO and to 10 mM in ethanol |
| Storage | Store at RT |
| IUPAC Name | (1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-(2-chlorophenyl)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,9b,10,11-decahydro-1H-indeno[5,4-f]quinoline-1-carboxamide |
| InChI | InChI=1S/C26H33ClN2O2/c1-25-14-12-18-16(8-11-22-26(18,2)15-13-23(30)29(22)3)17(25)9-10-19(25)24(31)28-21-7-5-4-6-20(21)27/h4-7,13,15-19,22H,8-12,14H2,1-3H3,(H,28,31)/t16-,17-,18-,19+,22+,25-,26+/m0/s1 |
| InChIKey | CTVXDPDUOKQBKZ-GFNRTWGOSA-N |
| SMILES | CC12CCC3C(C1CCC2C(=O)NC4=CC=CC=C4Cl)CCC5C3(C=CC(=O)N5C)C |
| Reference | <p> |
