Cl-C6-PEG4-C3-COOH

• CAT Number: I017329
• CAS Number: 2127391-58-4
• Molecular Formula: C18H35ClO6
• Molecular Weight: 382.92
• Purity: ≥95%
• Synonyms: 6-[2-[2-[2-(6-chlorohexoxy)ethoxy]ethoxy]ethoxy]hexanoic acid
• InChI: InChI=1S/C18H35ClO6/c19-9-5-1-2-6-10-22-12-14-24-16-17-25-15-13-23-11-7-3-4-8-18(20)21/h1-17H2,(H,20,21)
• InChIKey: DQFXVBKFPVKFQX-UHFFFAOYSA-N
• SMILES: C(CCCCl)CCOCCOCCOCCOCCCCCC(=O)O

Cl-C6-PEG4-C3-COOH is a PROTAC linker can be used in the synthesis of chloroalkane-containing PROTACs (HaloPROTACs)[1].

Reference

[1]. Ottis P, et al. Assessing Different E3 Ligases for Small Molecule Induced Protein Ubiquitination and Degradation. ACS Chem Biol. 2017 Oct 20;12(10):2570-2578.
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