Clavulanic Acid

• CAT Number: I024886
• CAS Number: 58001-44-8
• Molecular Formula: C8H9NO5
• Molecular Weight: 199.16
• Purity: 98%
• Synonyms: Clavulanic Acid; BRL14151; BRL-14151; BRL 14151; MM14151; MM-14151; MM 14151
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: 4°C, protect from light, stored under nitrogen
• IUPAC Name: (2R,3Z,5R)-3-(2-Hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• InChI: InChI=1S/C8H9NO5/c10-2-1-4-7(8(12)13)9-5(11)3-6(9)14-4/h1,6-7,10H,2-3H2,(H,12,13)/b4-1-/t6-,7-/m1/s1
• InChIKey: HZZVJAQRINQKSD-PBFISZAISA-N
• SMILES: O=C([C@@H](/C(O[C@]1([H])C2)=C/CO)N1C2=O)O

Clavulanate Potassium (Cat No.: I024886) is an oxy penicillate β-lactamase inhibitor composed of a β-lactam ring and a hydrogenated isoxazole ring. It is a suicide enzyme inhibitor agent. Clavulanate Potassium has only weak antibacterial activity but can firmly bind to most β-lactamases to form irreversible conjugates. It has a strong and broad-spectrum inhibitory effect on β-lactamase, not only on the enzymes of Staphylococcus, but also on the enzymes produced by a variety of Gram-negative bacteria, so it is an effective β-lactamase Inhibitor.

Reference

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