Clazuril

For research use only. Not for therapeutic Use.

  • CAT Number: M002614
  • CAS Number: 101831-36-1
  • Molecular Formula: C17H10Cl2N4O2
  • Molecular Weight: 373.19
  • Purity: ≥95%
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Clazuril(Cat No.:M002614)is a broad-spectrum anticoccidial agent used primarily in veterinary medicine to prevent and treat coccidiosis in poultry and livestock. It targets Eimeria species, the causative agents of the disease, by disrupting their intracellular development and replication. Clazuril’s high efficacy and long-acting properties make it effective with minimal doses, reducing the parasite burden and supporting animal health. Its safety profile and compatibility with feed additives enhance its utility in farm management. Clazuril plays a crucial role in improving productivity and controlling parasitic infections in animal husbandry.


Catalog Number M002614
CAS Number 101831-36-1
Synonyms

Clazurilum; Clazurilo

Molecular Formula C17H10Cl2N4O2
Purity ≥95%
Target Parasite
Storage Desiccate at -20C
IUPAC Name 2-[2-chloro-4-(3,5-dioxo-1,2,4-triazin-2-yl)phenyl]-2-(4-chlorophenyl)acetonitrile
InChI InChI=1S/C17H10Cl2N4O2/c18-11-3-1-10(2-4-11)14(8-20)13-6-5-12(7-15(13)19)23-17(25)22-16(24)9-21-23/h1-7,9,14H,(H,22,24,25)
InChIKey QUUTUGLQZLNABV-UHFFFAOYSA-N
SMILES C1=CC(=CC=C1C(C#N)C2=C(C=C(C=C2)N3C(=O)NC(=O)C=N3)Cl)Cl
Reference

<p>
<span style=”font-family:arial,helvetica,sans-serif;”><span style=”font-size:12px;”>1. J Vet Pharmacol Ther. 2018 Apr;41(2):184-194. doi: 10.1111/jvp.12450. Epub 2017 Aug 17.Review of triazine antiprotozoal drugs used in veterinary medicine.Stock ML(1), Elazab ST(1)(2), Hsu WH(1).</span></span></p>
<p>
<span style=”font-family:arial,helvetica,sans-serif;”><span style=”font-size:12px;”>Triazines are relatively new antiprotozoal drugs that have successfully controlled coccidiosis and equine protozoal myeloencephalitis. These drugs have favorably treated other protozoal diseases such as neosporosis and toxoplasmosis. In this article, we discuss the pharmacological characteristics of five triazines, toltrazuril, ponazuril, clazuril, diclazuril, and nitromezuril which are used in veterinary medicine to control protozoal diseases which include coccidiosis, equine protozoal myeloencephalitis, neosporosis, and toxoplasmosis.<br />
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2.</span></span><span style=”font-family: Arial, sans-serif; font-size: 13px; font-variant-ligatures: normal; orphans: 2; widows: 2;”>Vanparijs, O., et al. &quot;Clazuril: a new anticoccidial agent for pigeons.&quot;&nbsp;</span><i style=”font-family: Arial, sans-serif; font-size: 13px; font-variant-ligatures: normal; orphans: 2; widows: 2;”>Tijdschrift voor Diergeneeskunde</i><span style=”font-family: Arial, sans-serif; font-size: 13px; font-variant-ligatures: normal; orphans: 2; widows: 2;”>&nbsp;113.4 (1988): 190-194.</span></p>

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