Clemastine Fumarate

• CAT Number: A001062
• CAS Number: 14976-57-9
• Molecular Formula: C25H30ClNO5
• Molecular Weight: 460.00
• Purity: ≥95%
• Synonyms: Agasten; Mecloprodine; Aloginan; Xolamin
• Target: Histamine Receptor
• Solubility: Soluble in DMSO > 10 mM
• Storage: -20°C
• IUPAC Name: (E)-but-2-enedioic acid;(2R)-2-[2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl]-1-methylpyrrolidine
• InChI: InChI=1S/C21H26ClNO.C4H4O4/c1-21(17-7-4-3-5-8-17,18-10-12-19(22)13-11-18)24-16-14-20-9-6-15-23(20)2;5-3(6)1-2-4(7)8/h3-5,7-8,10-13,20H,6,9,14-16H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1+/t20-,21-;/m1./s1
• InChIKey: PMGQWSIVQFOFOQ-YKVZVUFRSA-N
• SMILES: C[C@@](C1=CC=CC=C1)(C2=CC=C(C=C2)Cl)OCC[C@H]3CCCN3C.C(=C/C(=O)O)\C(=O)O

Clemastine Fumarate（Cat No.:A001062）is a first-generation antihistamine that works by blocking H1 receptors, effectively reducing symptoms of allergic reactions such as itching, runny nose, sneezing, and watery eyes. It is commonly used to treat conditions like allergic rhinitis, hay fever, and urticaria. Clemastine Fumarate is known for its sedative properties due to its ability to cross the blood-brain barrier, making it useful in managing severe allergy symptoms. In research, it has gained interest for its potential neuroprotective effects in neurodegenerative diseases such as multiple sclerosis.