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21898-19-1-Clenbuterol Hydrochloride Clenbuterol Hydrochloride

Clenbuterol Hydrochloride

For research use only. Not for therapeutic Use.

  • CAT Number: R005984
  • CAS Number: 21898-19-1
  • Molecular Formula: C12H18Cl2N2O • HCl
  • Molecular Weight: 313.7
  • Purity: ≥95%
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Related Small Molecules: (3,5-DICHLORO-PHENYL)-METHANESULFONYL CHLORIDE     (-)-(3S)-3-Hydroxy Quinine     5-(CHLORO-DIFLUORO-METHYL)-ISOXAZOLE    

Clenbuterol Hydrochloride (Cat.No:R005984) is a sympathomimetic β2-adrenoceptor agonist that has been used as a bronchodilator in the treatment of pulmonary diseases such as asthma. At higher doses, clenbuterol acts as an anabolic steroid, favoring skeletal muscle protein synthesis at the expense of fat deposition.


Catalog Number R005984
CAS Number 21898-19-1
Synonyms

4-Amino-3,5-dichloro-α-[[(1,1-dimethylethyl)amino]methyl]benzenemethanol; NAB-365Cl; Spiropent; Ventipulmin;

Molecular Formula C12H18Cl2N2O • HCl
Purity ≥95%
Target Adrenergic Receptor
Solubility Soluble in DMSO
Storage Store at -20°C
IUPAC Name 1-(4-amino-3,5-dichlorophenyl)-2-(tert-butylamino)ethanol;hydrochloride
InChI InChI=1S/C12H18Cl2N2O.ClH/c1-12(2,3)16-6-10(17)7-4-8(13)11(15)9(14)5-7;/h4-5,10,16-17H,6,15H2,1-3H3;1H
InChIKey OPXKTCUYRHXSBK-UHFFFAOYSA-N
SMILES CC(C)(C)NCC(C1=CC(=C(C(=C1)Cl)N)Cl)O.Cl
Reference

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1:Clenbuterol Hydrochloride. Al-Majed AA, Khalil NY, Khbrani I, Abdel-Aziz HA.Profiles Drug Subst Excip Relat Methodol. 2017;42:91-123. doi: 10.1016/bs.podrm.2017.02.002. Epub 2017 Mar 31. PMID: 28431781<br />
2:Selection and Application of ssDNA Aptamers against Clenbuterol Hydrochloride Based on ssDNA Library Immobilized SELEX. Duan N, Gong W, Wu S, Wang Z.J Agric Food Chem. 2017 Mar 1;65(8):1771-1777. doi: 10.1021/acs.jafc.6b04951. Epub 2017 Feb 21. PMID: 28161951<br />
3:Detection of clenbuterol hydrochloride residuals in pork liver using a customized surface plasmon resonance bioanalyzer. Hu J, Chen R, Wang S, Wang T, Zhao Y, Li J, Hu X, Liang H, Zhu J, Sun X, Ma L, Jiang M.PLoS One. 2015 Mar 23;10(3):e0122005. doi: 10.1371/journal.pone.0122005. eCollection 2015. PMID: 25799327 Free PMC Article<br />
4:Highly sensitive fluorescent probe for clenbuterol hydrochloride detection based on its catalytic oxidation of eosine Y by NaIO4. Liu J, Liu ZB, Huang Q, Lin CQ, Lin X.J Fluoresc. 2014 Sep;24(5):1495-501. doi: 10.1007/s10895-014-1435-7. Epub 2014 Aug 27. PMID: 25155629<br />
5:Studies on binding interactions between clenbuterol hydrochloride and two serum albumins by multispectroscopic approaches in vitro. Wang Q, Zhang S.Luminescence. 2014 Aug;29(5):492-9. doi: 10.1002/bio.2574. Epub 2013 Sep 13. PMID: 24030872<br />
6:Rapid screening of clenbuterol hydrochloride in chicken samples by molecularly imprinted matrix solid-phase dispersion coupled with liquid chromatography. Qiao F, Du J.J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Apr 1;923-924:136-40. PMID: 23500358<br />
7:[Terahertz time-domain spectroscopy of Clenbuterol hydrochloride]. Chen XA, Hou DB, Huang PJ, Kang XS, Zhang GX, Zhou ZK.Guang Pu Xue Yu Guang Pu Fen Xi. 2011 Dec;31(12):3206-9. Chinese. PMID: 22295760<br />
8:Solid substrate-room temperature phosphorimetry for the determination of residual clenbuterol hydrochloride based on the catalysis of sodium periodate oxidizing eosine Y. Liu J, Zeng L, Li Z, Gao F, Huang X, Li F, Lin H.Anal Chim Acta. 2009 Apr 6;638(1):69-74. doi: 10.1016/j.aca.2009.02.007. Epub 2009 Feb 12. PMID: 19298881<br />
9:[Use of ultrasensitive time-resolved fluoroimmunoassay for rapid detection of clenbuterol hydrochloride in urine]. Shi J, Huang B, Zhang LF, Mi XL, Xu GR, Jin J.Wei Sheng Yan Jiu. 2006 Nov;35(6):798-801. Chinese. PMID: 17290771<br />
10:[Enantiomeric resolution of clenbuterol hydrochloride using (2R, 3R)-Dicyclohexyl tartrate impregnated thin layer chromatography]. Yu J, Liu S, Huang K, Jiao F, Peng X.Se Pu. 2005 Nov;23(6):687. Chinese. No abstract available. PMID: 16499011

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