For research use only. Not for therapeutic Use.
Clevudine(Cat No.:L034499)is a potent antiviral agent used in the treatment of chronic hepatitis B virus (HBV) infection. As a nucleoside analog, it inhibits HBV DNA polymerase, effectively suppressing viral replication. Clevudine has demonstrated a prolonged antiviral effect due to its sustained activity within hepatocytes, reducing viral load even after discontinuation. With oral bioavailability and a favorable safety profile, it offers a convenient treatment option for HBV management. Ongoing research explores its potential in combination therapies, aiming to enhance efficacy and reduce resistance in chronic HBV treatment strategies.
Catalog Number | L034499 |
CAS Number | 69256-17-3 |
Molecular Formula | C10H13FN2O5 |
Purity | ≥95% |
IUPAC Name | 1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione |
InChI | InChI=1S/C10H13FN2O5/c1-4-2-13(10(17)12-8(4)16)9-6(11)7(15)5(3-14)18-9/h2,5-7,9,14-15H,3H2,1H3,(H,12,16,17)/t5-,6+,7-,9-/m1/s1 |
InChIKey | GBBJCSTXCAQSSJ-JVZYCSMKSA-N |
SMILES | CC1=CN(C(=O)NC1=O)[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)F |